Everything You Need to Know About EstroG-100®

For many women, the transition into perimenopause and menopause can feel overwhelming. Hot flashes, night sweats, insomnia, mood swings, and joint aches can creep in and affect daily life. While hormone replacement therapy (HRT) has traditionally been the “go-to” option, not everyone can — or wants to — take hormones. That’s why researchers have been looking for safe, natural alternatives that actually work.

One of the most exciting breakthroughs? EstroG-100® — a plant-based, clinically tested herbal blend that’s gaining worldwide attention.

In this article, we’ll break down exactly what EstroG-100® is, how it works, what the science says, and why it may be the safest, most effective natural support for menopause relief available today.

What Is EstroG-100®?

EstroG-100® is a patented herbal complex made from three traditional medicinal plants used for centuries in Korea and China:

• 1️⃣ Cynanchum wilfordii
  
• 2️⃣ Phlomis umbrosa
  
• 3️⃣ Angelica gigas

These roots have long been prized in Eastern medicine for supporting women’s health, energy, and vitality. EstroG-100® standardizes these ingredients into a reliable formula that has been tested in multiple clinical trials.

Clinical Effectiveness: What the Research Shows

Korean Clinical Trial

In a randomized, double-blind, placebo-controlled trial, women aged 40–70 who took EstroG-100® for 12 weeks experienced:

• Significant reductions in hot flashes, insomnia, fatigue, joint pain, and vaginal dryness
  
• No negative changes in hormone levels, weight, or endometrial thickness

U.S. Study

Another trial in the United States tested EstroG-100® across White Hispanic, non-Hispanic, and African American women. Results showed:

• A dramatic drop in menopausal symptom scores (Kupperman Menopausal Index)
  
• Improvements in mood swings, nervousness, fatigue, and vaginal dryness compared to placebo

Indian Study (2023)

A newer single-arm study found:

• Relief across somatic, urogenital, and psychological symptoms
  
• 96.5% of women reported satisfaction
  
• No side effects reported

Safe, Hormone-Free Relief

Unlike hormone therapy, EstroG-100® is:

• Hormone-free — it does not bind to estrogen receptors or stimulate estrogen-sensitive tissues
  
• Non-toxic — safety confirmed in toxicology studies with no adverse effects
  
• Side-effect free — clinical trials report no significant negative changes in body weight, blood pressure, or labs

This makes it a compelling option for women who cannot (or prefer not to) use hormone replacement therapy.

How Does EstroG-100® Work?

Instead of adding hormones, EstroG-100® works by:

• Balancing neurotransmitters that affect mood and sleep
  
• Reducing inflammation and oxidative stress linked to joint pain and fatigue
  
• Supporting bone density and overall vitality

This means it can bring relief across a wide spectrum of symptoms, not just hot flashes.

Why EstroG-100® Stands Out

Here’s what makes EstroG-100® unique in the world of menopause supplements:

✅ Backed by multiple clinical trials in different countries and populations
✅ Targets multiple symptoms, not just one or two
✅ Hormone-free and safe for long-term use
✅ Derived from plants with centuries of safe use in traditional medicine

Who Might Benefit Most?

EstroG-100® could be an excellent fit for women who are:

• In perimenopause or menopause
  
• Experiencing sleep issues, mood swings, hot flashes, or joint pain
  
• Unable or unwilling to take hormone replacement therapy
  
• Looking for a natural, multi-symptom solution with strong scientific backing

Real-World Usage

Many women report life-changing relief with EstroG-100®. And when it’s paired with advanced delivery methods — like micelle-liposomal technology in Purality Health’s MenoPLUS — the absorption and effectiveness are enhanced even further.

With MenoPLUS, EstroG-100® is delivered in a way your body can actually use, so you feel the difference.

Conclusion

EstroG-100® isn’t just another herbal supplement — it’s one of the most researched, trusted, and safe natural solutions for menopause relief available today. Backed by multiple clinical trials and loved by women worldwide, it offers hormone-free support for hot flashes, sleep troubles, fatigue, joint pain, and more.

Want to see how you can get the most out of EstroG-100®? Learn more about how Purality Health’s MenoPLUS makes this powerful formula even more effective — and start feeling like you again.

References:

Korean Study: https://pubmed.ncbi.nlm.nih.gov/21887807/ 

U.S. Study: https://www.researchgate.net/publication/51615337_The_Effect_of_Herbal_Extract_EstroG-100_on_Pre-_Peri-_and_Post-Menopausal_Women_A_Randomized_Double-blind_Placebo-controlled_Study 

Indian Study: https://pubmed.ncbi.nlm.nih.gov/38504729/

More Studies & Info: https://estrog100.com/en/clinical-studies